

For Youth, You Need Collagen
A key indicator of skin aging...
...is the decline in collagen levels.
Collagen is the most abundant and widely distributed functional protein in the human body. It makes up approximately 70% of the skin's dermis, maintaining elasticity, resilience, and structural stability.
Collagen synthesis peaks around age 20, after which the body loses about 1%–1.5% annually. As we age, the capacity for collagen synthesis gradually declines while the rate of breakdown accelerates.
Fine lines, sagging, loss of volume, and blurred contours...
...are all signs of collagen loss.

Making Collagen Visible
Yaohai Novagen is a science-driven skincare company rooted in biosynthesis technology.
"Biosynthesis for Natural Beauty" is at the core of our mission.
Leveraging Yaohai Bio’s decade-plus background in pharmaceutical R&D, we approach our work with humility, using cutting-edge biotechnology to decode the genetic secrets of natural beauty and help skin reveal a healthy, vibrant radiance.

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Core Patented Ingredient
Our Recombinant Humanized Type III Collagen
What Makes It Different?
410
No animal-derived sources; no simple splicing together of fragments
Enabling the skin to generate collagen as if naturally produced
Virus-free, non-cytotoxic, and hypoallergenic
Engineered through a complex design comprising 410 amino acids
Completely non-repetitive sequence
Like building a LEGO castle where no two bricks are identical;
Like brewing a seemingly simple hot soup that incorporates 410 different ingredients;
…
100%
Identical amino acid sequence to human collagen
Verified against the NCBI (National Center for Biotechnology Information) database—one of the world's largest life science databases
Resulting in 100% sequence homology
High Quality
Pharmaceutical-grade fermentation, purification, and production facilities, combined with rigorous quality standards, ensure a premium-quality ingredient.
The *Pichia pastoris* expression system, combined with a complex sequence design, creates a stable triple-helix structure—unlocking the secret to skin rejuvenation.
High purity, high stability, high activity
Low
Hypoallergenic
Passed GB/T 16886 biological evaluation testing for medical devices
16 tests ensuring skin safety
As the year draws to a close
Echo Orea [Nuo Collagen Series] makes its grand debut
Full product line holds Class II medical device registration certificates
Clean, safe, and low-irritation
Repair and nourish simultaneously
Skincare for sensitive skin doesn't have to feel like walking on thin ice
In the new year, may you have fewer worries and fewer fine lines
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