Recombinant proteins are proteins obtained by applying recombinant DNA technology. The host cells used to produce recombinant proteins are mainly Escherichia coli cells (prokaryotic expression system) and yeast cells (eukaryotic expression system).
Recombinant proteins have been widely used in the fields of therapeutic recombinant protein drugs and drug carriers, preventive recombinant protein vaccines, immunoassay reagents, diagnostic reagent development, etc., and play an important role in most popular research directions such as antibody drug target screening, CAR-T cell therapy, CDC conjugate drugs, enzyme preparations, influenza virus proteins and cytokines.
In the field of recombinant protein services, Yaohai Bio can provide CMC one-stop services for various types of recombinant proteins, including cytokines, carrier proteins, recombinant peptides, enzymes, allergens, VLPs, vaccines and other types of recombinant proteins.
Yaohai Bio is committed to developing a recombinant protein CDMO service platform with robust processes, which can provide customers with full life cycle services from genetic engineering bacteria construction, strain library establishment, small-scale process development/optimization, pilot process amplification, IND application and clinical sample preparation, quality standard establishment, analytical method development/validation, quality management system establishment, NDA registration application and commercial production (MAH), to meet customers' commercial needs at different stages of recombinant protein drug product development. With rich experience in process development and production, we are committed to providing fast and high-quality services to customers' project entrustment.
We have comprehensive and diversified experience in recombinant protein process development, including:
-Cytokines
-Carrier proteins
-Recombinant polypeptides
-Recombinant enzymes
-Allergens
-VLPs
-Vaccines
Advanced process development concepts
Based on the requirements of the Quality by Design (QbD) concept, through DoE experimental process design, with CQA (critical quality atttibute) as the starting point, we confirm the critical process parameters (CPP) to achieve a stable process with high yield and high yield.
Mature platform technology
-Mature label-free protein process development capabilities, reducing process steps, improving protein purity, and ensuring that process impurities and product impurity residues are qualified.
-Realize the localization of key materials and equipment, save costs, and platform technology can quickly respond to project needs and shorten process development time.
hotline:0523-86285566 (ext. 8900)
EMail:xumingyue@yaohaibio.cn
Copyright © Jiangsu Yaohai Novagen Bio-technology Co.,Ltd. - All Rights Reserved Web design